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Mantle cell lymphoma

3 associated genes
7 signs/symptoms

PROTEIN INTERACTIONS: 1

6-pyruvoyl-tetrahydropterin synthase deficiency

1 OMIM reference -
1 associated gene
No signs/symptoms info

Mantle cell lymphoma

6-pyruvoyl-tetrahydropterin synthase deficiency

ATM	(UniProt - OMIM)		PTS	(UniProt - OMIM)
CCND1	(UniProt - OMIM)
IGH	(UniProt)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ATM	(0.63)	PTS

Citations in the biomedical literature:

Mantle cell lymphoma		6-pyruvoyl-tetrahydropterin synthase deficiency
	Synonym(s): - LCM - MCL - Mantle zone lymphoma		Synonym(s): - Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: adult Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive

	External references: No OMIM references 1 MeSH reference: D020522		External references: 1 OMIM reference - 1 MeSH reference: C535325

Mantle cell lymphoma
	Very frequent - Hematologic / blood / lymphatic cancer - Lymphadenopathy / polyadenopathies Frequent - Anorexia - Asthenia / fatigue / weakness - Bone marrow / medullar infiltration - Splenomegaly - Weight loss / loss of appetite / break in weight curve / general health alteration
6-pyruvoyl-tetrahydropterin synthase deficiency
(no data available)